• Note: Investigation are shown since median ± SD.
• Abbreviations: RFS: reflux wanting get; RSI: reflux symptom index.

step three.3 Surgical outcomes

₂ (CT90 and L-SpO₂), and ESS scores decreased after UPPP surgery in 34 OSA patients. Moreover, both the RSI score and RFS decreased after treatment with UPPP.

• Note: Study try displayed as average ± SD.
• Abbreviations: AHI, apnea/hypopnea index; BMI, body mass index; CT90%, percentage of recording time when oxygen saturation of arterial blood<90%; ESS, Epworth Sleepiness Scale (range 0–24); L-SpO₂, lowest blood oxygen saturation during recording time; RFS, reflux finding score; RSI: reflux symptom index.

Patients whose AHI decreased by 50% from baseline and AHI <20 per hour after surgery were considered as surgical success. 20 The surgical success rate was % (). In 25 successful surgery patients, the RSI score and RFS were lower than before surgery, and the LPR prevalence changed immediately after successful UPPP surgery (Table 4).

• Note: Research is shown while the median ± SD.
• Abbreviations: RFS: reflux interested in get; RSI: reflux symptom list.

Figure 3A shows that all individual RSI variables improved significantly after surgery (P <.05), except for hoarseness (P = .054). When we compared the pre- and postsurgery individual RSI variables in patients in the successful or unsuccessful surgery group, all RSI variables improved significantly after successful surgery (P <.05, Figure 3B), except for hoarseness and postnasal drip (P = .117 and P = .052, respectively), but no RSI variables significantly changed after unsuccessful surgery (Figure 3C).

cuatro Discussion

This study investigated the effect of UPPP surgery for OSA on LPR symptoms based on patient responses to the RSI and RFS questionnaires. We found: (1) a close correlation between OSA and LPR: LPR is more prevalent in OSA patients than in the general population, and AHI and CT90 were positively and L-SpO₂ negatively correlated with LPR symptoms, and (2) UPPP surgery, especially when successful, significantly lowered the mean RSI score and RFS but also individual RSI variables.

The brand new coexistence regarding OSA which have LPR could have been advertised to own a prevalence from 20%–67%. 21, 22 Whether or not earlier in the day education couldn’t have demostrated an immediate relationships ranging from him or her, it recommended a prospective causative dating. 23 The efficiency indicate that the degree of OSA try relevant having LPR seriousness, men looking for women united states hence you will find an almost relationship between OSA and you may LPR. A relationships between the two you will describe the abilities, particularly, OSA causes inflammatory burns, reasonable intrathoracic tension, and you may leakages of your all the way down esophageal sphincter; consequently, LPR (Heartburn) results in harm to the fresh new esophagus, larynx, and you can pharynx mucosa along with laryngopharyngeal symptoms.

Anti-reflux therapy eters of OSA. 24 Simultaneously, other studies report that CPAP can reduce GER events and improve nocturnal GER symptoms in OSA patients. 20, 21 However, few studies report on the effect of surgical treatment for OSA on LPR. 25 UPPP is usually not the first choice of treatment in most patients with OSA compared to CPAP. If CPAP is refused or the obstructive plane is defined, surgery can be considered as a treatment for OSA, especially multilevel surgery. UPPP is indicated in patients who only have airway collapse at the level behind the palate, and our study included participants whose level of collapse was presumed to be in the oropharynx was in the oropharynx. The present study demonstrated that postoperative AHI, night-time SpO₂ (CT90 and L-SpO₂), the RSI score, and the RFS were greatly improved after surgery. Interestingly, when we compared the pre- and postsurgery changes in the mean RSI score and mean RFS among patients in the successful and unsuccessful surgery groups, the successful surgery group experienced a significant decrease in the RSI score and RFS, but there was only one significant difference (mean RFS) in the unsuccessful group. We proposed that successful UPPP surgery lowered RSI scores and RFSs, and unsuccessful surgery improved the RFS only.